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Millions of women suffer from vaginal dryness. They experience this when going through menopause or many years after that. However, a woman can have vaginal dryness at any age due to several reasons. One of the primary reasons is decreased estrogen levels. A female hormone, estrogen, helps in keeping the vaginal lining lubricated, thick, and elastic.

While vaginal dryness might not be a problem for some, but it has a considerable impact on the woman's sex life. Vaginal drying causes pain and discomfort while having sex. Fortunately, the market is flooded with several treatment options – both prescriptions and over-the-counter – to relieve vaginal dryness. HYALO GYN® is one such OTC treatment option.

What is HYALO GYN®?

HYALO GYN® is a uniquely formulated colorless, transparent, odorless, aqueous hydrating gel for addressing the vaginal dryness. A product of Fidia Farmaceutici S.p.A, HYALO GYN®, contains Hydeal-D®, a proprietary formation of hyaluronic acid (HA) formulated by FIDIA. Hyaluronic acid acts as the body’s natural water reservoir and maintains hydration of the skin. The vaginal lining also has a presence of natural HA, and Hydeal-D® aims at replenishing the hydration.

Benefits of HYALO GYN®

Using HYALO GYN® allows a patient to get relief from the first application itself. Some of the benefits of HYALO GYN® are
  • Non-hormonal hydrating gel
  • Relief from the first application itself
  • Stabilizes the vaginal pH
  • No unpleasant odor
  • No discoloring
  • No messy residue or build-up
  • Long-lasting hydration

Is HYALO GYN® Effective?

Fidia Farmaceutici S.p.A, the manufacturer of HYALO GYN®, conducted a clinical study in a representative group (80 patients) who used the cream for relief from vaginal dryness. These women applied one application every three days and found a reduction in their symptoms. The efficacy of the OTC gel is shown in the following tables

Table: Percentage of Subjects Reporting Burning Sensation


Initial Day 7Day 15Day 30
Absent7.5%23.7%53.8%53.8%
Slight 41.2%57.5%46.2%46.2%
Moderate40.0%18.8%0%0%
Considerable11.3%0%0%0%
Data: Fidia Farmaceutici S.p.A, study of HYALO GYN®

Table: Percentage of Subjects Reporting Itch Sensation


Initial Day 7Day 15Day 30
Absent38.7%62.5%82.5%88.8%
Slight 18.8%36.3%17.5%11.2%
Moderate32.5%1.2%0%0%
Considerable10.0%0%0%0%
Data: Fidia Farmaceutici S.p.A, study of HYALO GYN®

Table: Percentage of Subjects Reporting Dyspareunia


Initial Day 7Day 15Day 30
Absent35.6%55.7%64.1%67.9%
Slight 20.6%27.8%33.3%32.1%
Moderate34.2%16.5%2.6%0%
Considerable9.6%0%0%0%
Data: Fidia Farmaceutici S.p.A, study of HYALO GYN®

Side Effects

Hyaluronic acid is considered very safe and has few side effects. Since it is a naturally produced product in the body, an allergic reaction is very negligible, almost absent. That said, there a few side effects of HYALO GYN®
  • Rare cases of increased vaginal infection, when used during vaginal infection
  • Isolated incidences of increased irritation
  • There is evidence that specific cancer cells are sensitive to HA, and using supplements having HA can lead to increased growth in cancer cells. Hence, doctors ask the patient to avoid using it if they have a history of cancer or cancer
  • Effectiveness and safety of HYALO GYN® has not been studied in pregnant women
HYALO GYN® is an effective treatment against vaginal dryness, but like all drugs, both prescription and OTC, the GP or OB/GYN should be consulted before using HYALO GYN®.