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Heard a lot about digestive enzyme supplements and wanting to know more about it, then read on.

Digestive Enzyme Supplements

A complex protein, digestive enzyme is made by the human body to assist in breaking the food down to a size that can be easily absorbed by various organs.

While the pancreas is the major player when it comes to the production of digestive enzymes, some enzymes are also produced by mouth, small intestines, and stomach.

Digestive enzymes include:


  • Amylase — breaks down complex sugars into molecules like maltose
  • Lipase — breaks apart complex fats into glycerol and smaller fatty acid
  • Cholecystokinin —secreted by small intestine causing gallbladder contraction and bile production, as well as the production of digestive enzymes by the pancreas
  • Pepsin — breaks proteins present in foods like dairy products, eggs, and meat, into peptides
  • Trypsin — breaks protein down into amino acids
  • Lactase — breaks down lactose
Found naturally and sold as prescription drugs, digestive enzymes are also sold in the market as dietary supplements.

Available in a chewable tablet form or a pill, these contain one or more than one digestive enzymes supplements. Some are also sold along with probiotics.

Originally made to compensate people having pancreatic insufficiency, these digestive enzyme supplements can be purchased online and brick and mortar stores.

Best Time For Intake

The most appropriate time for taking the digestive enzyme supplement is right before consuming your food or during your meals. You can check the label for instructions in case you are not sure.

Generally, the ideal time is about 30 minutes before your meal or right before the meal.

Let’s have a look at some of the best digestive enzyme supplements.

Zenwise Health - Best Overall Supplement

Zenwise Health’s digestive enzyme supplement uses prebiotics, probiotics, and plant-based enzymes for providing optimal digestive health. This supplement includes vital digestive enzymes like amylase, lactase, and proteases.
Prebiotics and probiotics present in Zenwise Health’s supplement help in reducing diarrhea and IBS symptoms. These vegetarian-friendly capsules can be taken before each meal, which helps in digesting what you eat.

Spring Valley Enzyme Supplement – Budget-Friendly

If you pack your medicine cabinet with various OTC tablets to aid in proper digestion, and do not have enough bucks to get a new one, then don’t despair.
Enzyme supplement offered by Spring Valley’s is the most affordable supplement presently out there in the market. This supplement contains enzymes that are said to aid in better absorption of foods like protein and starches.

It also includes papaya extract, which does help in reducing symptoms of bloating, constipation, and heartburn. The addition of probiotics helps in promoting both immune and digestive health.

Garden of Life Digestive Supplement – Best IBS Supplement

The vegetarian supplement offered by Garden of Life contains enzymes that may aid in the reduction of IBS-C and IBS-D symptoms.
This supplement includes enzymes that aid in breaking down proteins, fats, and dairy products. The capsules also claim in successfully breaking down tough veggies like legumes and broccoli.

MAV Nutrition Digestive Enzymes - Best Supplement for Gas

Digestive enzyme supplements by MAV claims in aiding your intestines to break down food which causes gas.
Thanks to MAV’s supplements, you may enjoy super smoothies, high-fiber, and lean protein foods.

To be taken before each meal, these digestive supplements can help in reducing gas present in the stomach and reducing the painful feeling that one gets after large meals.

Healthy Digestives Enzyme Formula - Best Gluten Supplement

People who have celiac disease need to eliminate gluten from the diet.
Gluten sensitivity can also affect people who do not have celiac disease. It can cause bloating, diarrhea, nausea, and joint pain.

Healthy Digestive’s enzyme formula aids in breaking down gluten present in foods like pasta, grains, and salad dressings, which allows you to enjoy your food without any worries.

This formula is also helpful in breaking down foods like fibrous veggies.

Prior approval is required from your doctor before you start taking this supplement.

Rainbow Light Enzyme System - Best Vegan Supplement

A plant-based solution, the Advanced Enzyme System by Rainbow Light, is the best bet for vegans who want to enjoy their favorite food without any worries.
This botanical blend contains plant-sourced enzymes that help in breaking down complex carbs, fats, and protein which helps in less gas formation, less bloating, and better digestion.

It’s perfect for a diet that has a substantial amount of hard-to-digest high-fiber foods. This vegan formula contains peppermint and ginger which helps in cooling the stomach down.

Enzymedica Lacto - Best Supplement For Lactose Intolerance

Lactose intolerant people have a problem in effectively digesting the sugars present in milk due to lack of lactase enzyme.
Consumption of any diary product by these people can result in them having bloating, gas, and diarrhea.

While avoiding all forms of dairy products helps in eliminating the symptoms, but what does one do when they crave an occasional cheese pizza or ice cream. Enter Enzymedica’s Lacto enzyme.

This supplement focuses on lactose-intolerant people. This enzyme contains lactase that helps in breaking down sugars and other enzymes allowing proper digestion of carbs and fats. It may also aid in relieving symptoms of gas and bloating.

This vegan and gluten-free supplement are suitable for everyone.

Bottom Line

While digestive enzyme supplements are good, a prior discussion with your doctor will go a long way in addressing any symptoms that might arise from the ingestion of these supplements.